Pixels might not be RGB, maybe RBG or BRG .. put xlights into test mode and cycle through red, green, blue colours, you can either tell xlights the order of colour or configure it on most modern controllers.
Hmm. Didn’t know that about the different ones. Last year it was right and working well. Now my screen on the computer will show for instance all my lights to be blue with twinkle and outside they will be green with twinkle! Crazy! So how do I change this in xlights if this is a software issue?
You can change the orientation in Xlights or on the controller. In Xlights on the layout tab select the problem model. Under string properties change from RGB nodes to RBG nodes. I prefer to do this on the port configuration on my controllers