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Looks like you may have auto optimization enabled. When the sequence is being optimized in the background, then this can cause this issue. I turn off outo optimization as I have found it can cause crashes and bad performance with large sequences.burner said:Has anyone else had to do a save as with the new version, because the save function says that the file is in use? I had to do this on all my sequences after a slight channel change needed me to modify all my files.