I have LOR software running 2 X LOR DC boards and 7 X AVD boards in DMX mode all running nicely. A lot depends on what you want to do with your lights, but take your time.
It depends on the effect you want and location of RGB strips. if your strips are in the open make sure water proof. a defuser will give you a softer light and more blended colour where as naked led will be brighter and sharper and blending is not as great